FACTORS OF RESILIENCE TO ALZHEIMERS DISEASE AND RELATED DEMENTIAS AMONG LATINX: THE ROLE OF BILINGUALISM -…
Federal financial assistance recorded from USAspending. This is not a procurement contract.
Assistance award details
- Assistance award identifier
- ASST_NON_R00AG066932_075
- FAIN
- R00AG066932
- Recipient
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Awarding agency
- Department of Health and Human Services
- Funding agency
- Department of Health and Human Services
- Assistance listing (CFDA)
- 93.866
- Total obligated
- $936,203
- Period
- May 1, 2020 – Jan 31, 2026
- Fiscal year
- 2023
- Place of performance state
- NY
- Source file
- FY2023_All_Assistance_Full_20261006.zip
Description
FACTORS OF RESILIENCE TO ALZHEIMERS DISEASE AND RELATED DEMENTIAS AMONG LATINX: THE ROLE OF BILINGUALISM - PROJECT SUMMARY/ABSTRACT AS THE POPULATION AGES, LATINX COMMUNITIES, FAMILIES, AND HEALTHCARE SYSTEMS WILL BE CONFRONTED BY THE GROWING CRISIS OF ALZHEIMERâS DISEASE AND RELATED DEMENTIAS (ADRD). IDENTIFYING FACTORS THAT CONFER RESILIENCE TO ADRD AMONG AGING LATINX COMMUNITIES IS OF CRITICAL IMPORTANCE TO SUCCESSFULLY REDUCE DISPARITIES. SOME STUDIES FIND THAT BILINGUALS ARE AT REDUCED AD RISK COMPARED TO MONOLINGUALS, BUT OTHER STUDIES DO NOT FIND EVIDENCE OF A BILINGUAL ADVANTAGE. LITTLE ATTENTION HAS BEEN GIVEN TO WITHIN-GROUP DIFFERENCES AMONG BILINGUALS, SUCH AS AGE OF SECOND LANGUAGE (L2) ACQUISITION, PROFICIENCY, AND FREQUENCY OF LANGUAGE USE, AND HOW THESE DIFFERENCES 1) ARE RELATED TO COGNITIVE FUNCTION IN OLDER AGE, 2) IF THEY BUFFER THE EFFECTS OF NEUROPATHOLOGY ON COGNITIVE DECLINE, AND 3) HOW COGNITIVE DECLINE IN AD CAN INFLUENCE LANGUAGE USE AMONG BILINGUALS. DETERMINATION OF THE ASPECTS OF BILINGUALISM THAT CONFER RESILIENCE TO AD COULD LEAD TO NOVEL INTERVENTIONS TO MITIGATE COGNITIVE AGING AND ADRD DISPARITIES. THE OVERALL AIM OF THIS PROJECT IS TO DETERMINE WHETHER ASPECTS OF BILINGUALISM, INCLUDING AGE OF ACQUISITION, LANGUAGE USE, AND PROFICIENCY, BUFFER THE EFFECTS OF NEUROIMAGING MARKERS OF PATHOLOGY (I.E., AD BIOMARKERS AND CEREBROVASCULAR DISEASE) ON COGNITION AND COGNITIVE DECLINE WITHIN MIDDLE- AND OLDER-AGED LATINX ADULTS. THE K99 PHASE OF THIS STUDY SHOWED THAT EARLIER AGE OF ACQUISITION, GREATER L2 PROFICIENCY, AND GREATER DAILY BILINGUAL LANGUAGE USE, BUT NOT INCREASED CODE-SWITCHING, WERE POSITIVELY ASSOCIATED WITH EPISODIC MEMORY, LANGUAGE ABILITIES, AND ASPECTS OF EXECUTIVE FUNCTIONING, INDEPENDENT OF CONFOUNDING SOCIOCULTURAL FACTORS (I.E., EDUCATION, SOCIOECONOMIC STATUS, IMMIGRATION). IN THE R00 PHASE, THE RELATIONSHIP BETWEEN BILINGUALISM AND IMAGING MARKERS ON COGNITIVE DECLINE WILL BE EVALUATED (AIM 1) AND WE WILL EVALUA