A CROSS-NATIONAL COMPARATIVE STUDY ON CARDIOMETABOLIC RISK, EDUCATION, AND COGNITIVE AGING - PROJECT SUMMAR…
Federal financial assistance recorded from USAspending. This is not a procurement contract.
Assistance award details
- Assistance award identifier
- ASST_NON_R00AG070274_075
- FAIN
- R00AG070274
- Recipient
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Awarding agency
- Department of Health and Human Services
- Funding agency
- Department of Health and Human Services
- Assistance listing (CFDA)
- 93.866
- Total obligated
- $753,548
- Period
- Jul 1, 2023 – Mar 31, 2026
- Fiscal year
- 2023
- Place of performance state
- NY
- Source file
- FY2023_All_Assistance_Full_20261006.zip
Description
A CROSS-NATIONAL COMPARATIVE STUDY ON CARDIOMETABOLIC RISK, EDUCATION, AND COGNITIVE AGING - PROJECT SUMMARY ALZHEIMER'S DISEASES AND ALZHEIMER'S DISEASE-RELATED DEMENTIAS (AD/ADRD) IMPOSE SIGNIFICANT GLOBAL CHALLENGES THAT NECESSITATE RESEARCH TO IDENTIFY CRITICAL PROTECTIVE AND RISK FACTORS OF COGNITIVE HEALTH. RESEARCH FROM DEVELOPING COUNTRIES SHOWS THAT THE DECLINE IN AGE-SPECIFIC PREVALENCE AND INCIDENCE OF SEVERE COGNITIVE IMPAIRMENT AND DEMENTIA SINCE THE 1980S PARALLELS THE RISE IN EDUCATIONAL ATTAINMENT AND IMPROVEMENTS IN THE CONTROL OF CARDIOMETABOLIC RISK (CMR). HOWEVER, THE COMPLEX DYNAMICS OF EDUCATION, CMR, AND COGNITIVE HEALTH COMPLICATE EFFORTS TO PINPOINT SPECIFIC PATHWAYS FROM EDUCATION OR CMR TO COGNITIVE OUTCOMES. THE PROPOSED RESEARCH WILL USE REPRESENTATIVE LONGITUDINAL DATA FROM THE UNITED STATES HEALTH AND RETIREMENT STUDY AND ITS INTERNATIONAL SISTER STUDIES IN ENGLAND, CHINA, AND INDONESIA, AS WELL AS NEW DATA OBTAINED FROM THE HARMONIZED COGNITIVE ASSESSMENT PROTOCOL STUDIES TO SYSTEMATICALLY AND RIGOROUSLY DESCRIBE AND COMPARE THE CMR AND EDUCATIONAL PATTERNS OF COGNITIVE FUNCTION, COGNITIVE AGING, AND DEMENTIA IN FOUR COUNTRIES. THESE COUNTRIES COMPRISE ABOUT 25 PERCENT OF THE WORLD'S POPULATION, ARE AT DIFFERENT LEVELS OF ECONOMIC DEVELOPMENT AND STAGES OF NUTRITIONAL TRANSITION, AND REPRESENT A WIDE RANGE OF HISTORICAL, CULTURAL, SOCIAL, EPIDEMIOLOGICAL, AND MEDICAL CONTEXTS. THIS RESEARCH IS IMPORTANT BECAUSE THE CROSS-NATIONAL COMPARISON OF KEY PATTERNS OF COGNITIVE HEALTH WILL ENHANCE THE UNDERSTANDING OF HOW BROAD SOCIAL- ENVIRONMENTAL CONTEXTS, COUPLED WITH THEIR EMBEDDED INDIVIDUAL CHARACTERISTICS AND EXPERIENCES, AFFECT COGNITIVE HEALTH IN OLD AGE. TO ACCOMPLISH THIS RESEARCH GOAL, THE K99 PHASE WILL INVOLVE TRAINING IN NEUROPSYCHOLOGY, THE INTERNATIONAL CONTEXT OF HEALTH AND AGING, AND ADVANCED TECHNIQUES IN COMPARATIVE ANALYSIS USING LONGITUDINAL DATA. THIS TRAINING WILL TAKE PLACE AT THE CAROLINA POPULATION CENTER (CPC) AT