COMMUNITY EMPOWERMENT, VASCULAR RISK, AND ADRD DISPARITIES: TRANSLATING RESEARCH TO PUBLIC POLICY - BY 2050…
Federal financial assistance recorded from USAspending. This is not a procurement contract.
Assistance award details
- Assistance award identifier
- ASST_NON_R00AG083121_075
- FAIN
- R00AG083121
- Recipient
- TRUSTEES OF BOSTON UNIVERSITY
- Awarding agency
- Department of Health and Human Services
- Funding agency
- Department of Health and Human Services
- Assistance listing (CFDA)
- 93.866
- Total obligated
- $249,000
- Period
- Sep 1, 2023 – Feb 28, 2029
- Fiscal year
- 2026
- Place of performance state
- MA
- Source file
- FY2026_All_Assistance_Full_20261006.zip
Description
COMMUNITY EMPOWERMENT, VASCULAR RISK, AND ADRD DISPARITIES: TRANSLATING RESEARCH TO PUBLIC POLICY - BY 2050, RACIAL DISPARITIES WILL PERSIST AMONG THE PROJECTED 11 MILLION ADULTS WITH ALZHEIMERâS DISEASE AND RELATED DEMENTIAS (AD/ADRD). PRIOR RESEARCH LINKS FACTORS TO AD/ADRD, HIGHLIGHTING THE NEED FOR POLICY SOLUTIONS TO MITIGATE THE RACIALLY-PATTERNED CARDIOVASCULAR DISEASE (CVD) BURDEN THAT ACCELERATES AD/ADRD ONSET. ECONOMIC DISINVESTMENT PREVENTS MAJORITY-BLACK AND MAJORITY-POOR NEIGHBORHOODS FROM INVESTING IN THEIR LOCAL INFRASTRUCTURE. THESE ECONOMIC FACTORS LIMIT COMMUNITY ENGAGEMENT AMONG THE VERY GROUPS WHOSE CARDIOVASCULAR AND COGNITIVE HEALTH WOULD BENEFIT MOST FROM EFFECTIVE HEALTH POLICY. HOWEVER, IT IS NOT KNOWN HOW LOWER INVESTMENT AND DISENGAGEMENT CONTRIBUTE TO AD/ADRD DISPARITIES VIA EXCESS CVD RISK. THIS PROPOSED K99/R00 HARNESSES THE REASONS FOR GEOGRAPHIC AND RACIAL DIFFERENCES IN STROKE (REGARDS) STUDY, HEALTH AND RETIREMENT STUDY (HRS), AND ADMINISTRATIVE CLAIMS FROM MEDICARE BENEFICIARIES. FOR MY K99 PHASE, I WILL IDENTIFY INDICATORS OF LOWER ECONOMIC INVESTMENT OR SOCIAL DISENGAGEMENT THAT WORSEN AD/ADRD TRAJECTORIES AND WIDEN RACIAL DISPARITIES IN REGARDS AND HRS. THEN I WILL USE THESE RESULTS TO CALCULATE THE POPULATION ATTRIBUTABLE FRACTION OF LOWER INVESTMENT AND DISENGAGEMENT ON AD/ADRD AMONG MEDICARE BENEFICIARIES. DURING MY R00 PHASE, I WILL ANALYZE THE MEDIATING ROLE OF CVD IN ASSOCIATIONS OF COMMUNITY RESOURCES (ECONOMIC INVESTMENT AND SOCIAL ENGAGEMENT) AND INCIDENT AD/ADRD IN MEDICARE CLAIMS. FINALLY, I WILL UTILIZE THE CVD POLICY MODEL TO FORECAST NATIONWIDE COMMUNITY EMPOWERMENT POLICIES THAT REDUCE CVD RISK FACTORS FOR AD/ADRD UP TO THREE DECADES IN THE FUTURE. BUILDING UPON MY FOUNDATION OF DATA SCIENCE, CAUSAL INFERENCE, AND CVD EPIDEMIOLOGY, MY TRAINING PLAN CONSISTS OF NEW KNOWLEDGE DOMAINS: 1) AD/ADRD SCIENCE, 2) SPATIAL MODELING, 3) MEDICARE CLAIMS, AND 4) ESTIMATION OF PUBLIC HEALTH IMPACT ATTAINABLE WITH COMMUNITY IN