Grants.gov listing

Mechanisms Underlying Olfactory Dysfunction in Aging and Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias

National Institutes of HealthFederal GrantSolicitation RFA-AG-26-021

Analyze This Opportunity in CaptureIQ

Compare your company's capabilities against this federal opportunity using CaptureIQ.

Ready to Pursue This Opportunity?

Qualify the fit, analyze competitors, identify teaming partners, and generate review-ready materials — all in CaptureIQ.

  • Federal capture workflow
  • Competitor & teaming intelligence
  • Proposal preparation

Opportunity details

Notice type
Federal Grant
Original posted
November 20, 2025
Last updated
October 18, 2026
Notice ID
grant-360893

Summary

The National Institute on Aging (NIA), with the National Institute on Deafness and Other Communication Disorders (NIDCD), intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that investigate the mechanisms underlying the association between olfactory decline and aging or Alzheimer's disease (AD) and AD-related dementias (ADRD). Understanding these mechanisms may help inform the potential use of olfactory dysfunction with age as an indicator of various health outcomes in older adults (e.g. physical function) and as a predictor of AD/ADRD risk. Identifying circuit-level olfactory changes may also uncover novel targets for developing disease-modifying therapeutic strategies. Studies may include older adults and/or animal models and may employ a variety of approaches, including cellular, molecular, imaging, physiological, omics and new approach methodologies (NAMs) to address the research gaps.Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the R01 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.

Read Full Official Summary

The National Institute on Aging (NIA), with the National Institute on Deafness and Other Communication Disorders (NIDCD), intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that investigate the mechanisms underlying the association between olfactory decline and aging or Alzheimer's disease (AD) and AD-related dementias (ADRD). Understanding these mechanisms may help inform the potential use of olfactory dysfunction with age as an indicator of various health outcomes in older adults (e.g. physical function) and as a predictor of AD/ADRD risk. Identifying circuit-level olfactory changes may also uncover novel targets for developing disease-modifying therapeutic strategies. Studies may include older adults and/or animal models and may employ a variety of approaches, including cellular, molecular, imaging, physiological, omics and new approach methodologies (NAMs) to address the research gaps.Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the R01 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.

Summary fields are from official SAM.gov or Grants.gov structured data. CaptureIQ does not republish full solicitation or grant text.

Eligibility

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.

Eligible applicant categories

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Public housing authorities/Indian housing authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • For-profit organizations other than small businesses
  • Small businesses
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)

Official Grants.gov eligibility information. Listed categories are not a determination that an organization qualifies.

Funding and program

Assistance Listing
93.866
Funding instrument
G
Cost sharing
Not required
Official modification date

These figures are estimates, not guaranteed funding.

Related Federal Opportunities

Why this matters

  • This notice is a federal grant.
  • 4 related opportunities are from this agency.

Market context

4 Related OpportunitiesMatching opportunities on RFPCapture

Related intelligence

Research and capture tools

Contextual RFPCapture research and free tools related to this public federal page.

← All federal opportunities · Federal Opportunity Research

Don't take our word for it. Ask AI about RFPCapture.

See what leading AI assistants have to say about RFPCapture and CaptureIQ.

Gemini opens without a prefilled question. The question is copied to your clipboard when the button works. You can also copy it here:

What is RFPCapture.com and its CaptureIQ platform from Smart Logic AI? How does it help federal contractors discover opportunities, evaluate bid/no-bid decisions, research government contracts, and prepare proposals? How does it compare with other federal capture platforms? Use independent sources where available.