Grants.gov listing

NIH Director’s Pioneer Award (DP1 Clinical Trial Optional)

The NIH Director"s Pioneer Award supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH.

National Institutes of HealthFederal GrantSolicitation RFA-RM-27-001

Response deadline

Wed, Sep 9, 2026, 12:00 AM EDT
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Opportunity details

Notice type
Federal Grant
Original posted
June 29, 2026
Last updated
August 30, 2026
Notice ID
grant-360986

Summary

The NIH Director"s Pioneer Award supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigator"s research program or elsewhere. Applications in all topics relevant to the broad mission of NIH are welcome. Research may involve basic, translational, or clinical research. The NIH Director"s Pioneer Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.

Read Full Official Summary

The NIH Director"s Pioneer Award supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigator"s research program or elsewhere. Applications in all topics relevant to the broad mission of NIH are welcome. Research may involve basic, translational, or clinical research. The NIH Director"s Pioneer Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.

Summary fields are from official SAM.gov or Grants.gov structured data. CaptureIQ does not republish full solicitation or grant text.

Eligibility

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Eligible applicant categories

  • Special district governments
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Private institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Independent school districts
  • Public and State controlled institutions of higher education
  • State governments
  • City or township governments
  • County governments
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Small businesses
  • Public housing authorities/Indian housing authorities
  • For profit organizations other than small businesses
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

Official Grants.gov eligibility information. Listed categories are not a determination that an organization qualifies.

Funding and program

Assistance Listing
93.310
Funding instrument
Grant
Cost sharing
Not required
Estimated total program funding
8,000,000
Expected number of awards
8 (government estimate, not a guaranteed count)
Official modification date

Estimated total program funding is the government figure for the whole program, not an individual award ceiling. The expected number of awards is a government estimate, not a guaranteed count. These figures are estimates, not guaranteed funding.

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Why this matters

  • This notice is a federal grant.
  • The response deadline is 66 days away.
  • 4 related opportunities are from this agency.

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