Resource and Capacity Building to Advance the Science of Aggression across Species and Disciplines (R24 Clinical Trial Optional)

Summary

<p>The Office of Behavioral and Social Sciences Research seeks to advance its mission by soliciting applications to advance research on the mechanisms of aggressive behavior across species and disciplines, consistent with OBSSR’s Congressional authorization to develop and coordinate research on violent behavior. Aggressive behavior is associated with numerous chronic diseases, especially psychiatric and neurological conditions. Additional scientific resources and capacity are needed to accelerate and enhance research to address this public health challenge through improved mechanistic understanding, prevention, and treatment of aggressive behavior. Priority areas for this NOFO will include: naturalistic and ecologically valid experimental paradigms that can be applied analogously across both animal and human research to bridge disciplinary silos and translational gaps; improved measurement tools to catalyze progress and improve causal inference, rigor, and reproducibility; and cross-species data repositories (e.g., behavioral, brain, genetic, and physiological data) to accelerate research advances to improve human health and well-being. Priority approaches will include: team scien…

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