Integrated system for field, clinic and laboratory preparation of biological specimens for microscopy

Biological tissues collection is problematic and risky even under ideal conditions; when collection occurs in remote locations, or by minimally- trained personnel, as may occur in response to an emerging disease threat, risks are magnified. This proposal addresses this issue by developing a Field Fixation Unit (FFU) for specimen collection that utilizes single-use capsules pre-loaded with fixative. FFUs will fully secure the samples within the collection vial and guarantee that the sample is fully submerged within the fixative by simply depressing a plunger. This simplifies collection to enhance quality and consistency, while also reducing risk and personnel training.