Multiplexed Chemical, Biological, and Explosive Indicator Ticket

The primary objective of this proposal is to develop a human-readable liquid ticket to improve detection of CWAs and other threat agents; and evaluate its sensitivity, specificity and reproducibility to develop a new detection method that compares favorably against the existing M8/M9 paper. iSense has successfully demonstrated capability in developing customized indicator arrays for detection of TICs, CWAs, and explosive materials using a low cost, commercial off-the-shelf scanner.We will test the human-readable liquid ticket with a diverse set of CWAs and CWA simulants to measure the sensor performance in addition to a range of explosives and TICs.The proposed work will utilize an extremely sensitive and high dimensional colorimetric sensor array to develop a human-readable indicator ticket to detect and presumptively identify CWAs, explosives, and biomarkers for bioterrorism agents.iSense has extensive experience in developing and implementing colorimetric tickets for detection of both liquid and gaseous analytes.Our indicator library and knowledge of colorimetric chemical reactions have continued to grow over the years of research and development.With this extensive experience and expertise to develop a new colorimetric indicator ticket, we are confident to customize our sensor technology for a human-readable indicator ticket.