Epic Allies: A smartphone app for ART uptake and adherence among YMSM

DESCRIPTION provided by applicant Men who have sex with men MSM account for nearly two thirds of all new HIV infections in the United States US and young MSM YMSM are the only risk group experiencing an increase in HIV incidence After diagnosis many YMSM do not enter medical care get prescribed antiretroviral therapy ART adhere to ART regimens or achieve viral suppression Novel theory based interventions that optimize engagement in care ART uptake and ART adherence for HIV YMSM are urgently needed to achieve both individual and public health benefits Our study will evaluate the efficacy Epic Allies a theory based mobile phone application app that utilizes game mechanics and social networking features to improve engagement in care ART uptake ART adherence and viral suppression rates among HIV YMSM Social networking technologies enhance support and reduce social isolation while game mechanics engage users to motivate and sustain behavior change High mobile phone ownership among YMSM supports using intervention tools based in these familiar available technologies The app addresses the most common engagement and adherence barriers among youth is tailored for the target population and is customizable for individual users Epic Allies targets HIV YMSM aged who are new to care naive or non adherent to ART Funded by the National Institutes of Health through a Phase I SBIR application we worked with programmers and designers at Caktus Consulting Group to develop and test the Epic Allies prototype and found it acceptable among a sample of HIV YMSM Our current Phase II proposal has aims Aim Refine Epic Allies for use in a clinic based trial and expand the scope of the developed app to address engagement in care and ART uptake Enhancements to the social networking features of the app will be made to ensure the communication and support needs of youth who are not currently on ART and those new to care are met To inform these changes we will conduct in depth usability interviews with YMSM not currently on ART and new to care Aim Test Epic Allies app among HIV YMSM recruited from Adolescent Trials Network ATN sites We will conduct a arm randomized controlled trial with measures at baseline and months Primary outcome measures will include engagement in care ART uptake medication adherence and viral load suppression Aim Conduct a process evaluation of Epic Allies including intervention acceptability impact and long term sustainability Qualitative in depth exit interviews n wil evaluate Epic Alliesandapos acceptability with the target population and its potential to improve engagement in care uptake of ART and adherence This project has high public health impact as it will address the current gap in scientific knowledge regarding how to best assist YMSM who are newly diagnosed with HIV and those who have adherence difficulties in order to improve medical psychological and public health outcomes Moreover the creation of a novel technology based adherence tool could be easily adapted for other highly prevalent and costly chronic diseases PUBLIC HEALTH RELEVANCE Engagement in care antiretroviral ART uptake and medication adherence is crucial for youth diagnosed with HIV in order to improve individual and public health outcomes HIV youth demonstrate lower rates of ART use higher loss to follow up more difficulty with strict daily medication adherence and ultimately worse clinical outcomes compared to adults Young HIV men who have sex with men YMSM face additional barriers to care from added negative social and psychological challenges associated with their sexual identity Epic Allies is a marketable novel mobile phone application app that utilizes game mechanics and social networking features to improve engagement in care ART uptake and medication adherence among HIV YMSM