Technology to Regulate Circadian Rhythm for Health and Performance

We propose a wearable, dual-use neurotechnology device. The Personal Brainwave Headband, driven by tablet or smartphone, is designed for noninvasive closed-loop acoustic stimulation, to permit improved circadian regulation. It will measure brain electrical activity from scalp overlying four key sectors of cortex, perform high-resolution spectral analysis of the signals, and use software algorithms to translate dominant brain frequencies into audible tones of changing pitch and timing. Resonance between brainwaves and audible tones facilitates self-optimization, manifesting as greater left-right hemispheric symmetry and more optimized ratios of energy between low and high frequencies of brain electrical activity. The net result of brain self-optimization will be more restful sleep. Preliminary data demonstrate efficacy of the approach when using external amplifiers and a laptop computer configuration, to support symptom reduction in insomnia, PTSD, TBI, and other conditions. The device will also have functionality for regular use in a monitor-only mode to enable identification of brain states associated with vulnerability (BSAV"s). BSAV"s (to be studied in Phase II) are those brain activity patterns (combinations of asymmetry and suboptimal ratios of energy between low and high frequencies) that are associated with a higher likelihood of experiencing emotional disturbance, or demonstrating compromised performance or maladaptive behavior.