SBIR/STTR Research Award
Non-invasive Detection System for Assessment of Oxidative Status
Award amount
$499,889Program and phase
SBIR · Phase IIAward year
2014Award details
- Awarding agency
- Department of Defense
- Branch
- Army
- Recipient company
- CHROMOLOGIC LLC
- Proposal award date
- 2014-01-27
- Contract end date
- 2015-01-26
- UEI
- D9EVNTKKWLF3
- Solicitation number
- 2012.2
- Topic code
- A12-097
Research abstract
To address the Armys need for a non-invasive, compact, robust system to monitor the oxidative status of military personnel, ChromoLogic (CL) proposed and demonstrated during Phase I a OCular Oxidative Stress Monitor (OCOSMO) system based on non-invasive optical measurements of oxidative stress biomarkers that are expressed within the aqueous humor (eye). By building multiple generations of OCOSMO prototypes and performing in vitro tests, CL demonstrated for the first time that cost-effective non-invasive monitoring of oxidative stress biomarkers in real-time is highly feasible. A high specificity panel of biomarkers was identified for determining oxidative stress caused from exercise. Tests with the OCOSMO prototypes showed that these biomarkers can be identified with sensitivity >10x the clinical level needed. In Phase II, CL plans to develop a complete OCOSMO prototype and perform detailed pre-clinical and clinical validation of the technology.
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Mitigation of Ionizing Irradiation-Induced Intestinal Damage by Second-Generation Probiotic LR-IFN-β
- Membrane-based AWE Device (MAWED)
- Ceramic membrane based portable oxygen generator (CEMPOG)
- CRISPR-based Assay for Portable Tropical Infection Diagnosis (CAPTIN-D)
- Wearable Heat Related Injury Risk Analysis (WHERA) system Resubmission
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Detection of Urinary Biomarkers for Assessment of Oxidative Status
- Non-invasive Detection System for Assessment of Oxidative Status
Research funding history
93 SBIR/STTR records share this UEI (2007–2025). Reported award amounts total $49,103,552. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Defense, Department of Health and Human Services, National Aeronautics and Space Administration, Department of Energy