SBIR/STTR Research Award

SBIR Phase I: Evaluating the Feasibility of a HAA-Meter for Affordable, Onsite Monitoring of Haloacetic Acids in Drinking Water Plants with Advanced Machine Learning Chromatographic Interpretation

Award identifier 22e774f4a9f7b022179e9d9612d687b76985fff5e0752b3dd11ee7ac6051ee4eAwarding agency Department of Health and Human Services · National Institutes of Health

Award amount

$309,285

Program and phase

SBIR · Phase I

Award year

2025

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Award details

Awarding agency
Department of Health and Human Services
Branch
National Institutes of Health
Recipient company
Foundation Instruments, Inc.
Proposal award date
2025-09-01
Contract end date
2026-02-28
UEI
D9CQM2L2N2M9
Solicitation number
PA24-245
Topic code
R

Research abstract

PROJECT SUMMARY/ABSTRACT Research has suggested that there is an increased risk of cancer associated with long-term exposure to drinking water containing halogenated disinfection by-products (DBPs). Haloacetic acids (HAAs) are the second most common class of halogenated DBPs formed during water chlorination. Every year, thousands of drinking water treatment plants (WTPs) struggle with HAAs compliance issues often allocating significant portions of the operating budget towards electrical and chemical means to minimize formation of the DBPs. Unfortunately, most WTP operators adjust treatment processes without having on-site, real-time HAAs concentration data to base their decisions on, leading to excess chemical and energy usage and higher operating costs. Standard USEPA methods are suitable for quarterly compliance monitoring HAAs, but are often too expensive, complex, and not well-suited for continuous real-time monitoring. This Small Business Innovation Research Phase I project specific aims will focus on evaluating the technical feasibility of an affordable, on-site, HAA-Meter with an integrated machine learning algorithm that will allow automated chromatographic data interpretation and analysis. The proposed technology will drastically reduce the cost of current available technology by half, providing WTPs an affordable option for onsite HAAs monitoring and analysis. We will achieve this by integrating concepts, techniques, and components recently derived from our NSF and NIEHS SBIR Phase II research projects. Additionally, the machine learning model will enable automated interpretation of the chromatograms, evaluation of data quality, and provide Total HAAs concentrations to the WTP operator with no user intervention, thus dramatically simplifying the analysis. The HAA-Meter, will provide WTPs the ability to respond in real-time to minimize HAAs concentrations produced at the WTP and in the distribution system. This lowers the risk of cancer from HAAs for communities across the United States, large and small, rural and metro. The HAA-Meter analyzer will be fully automated and designed for operators with skill levels consistent with typical WTP personnel. Ultimately, the result of this SBIR proposal will be to determine the technical feasibility of reducing costs and establishing a novel machine learning algorithm to fully automate data analysis and interpretation of the HAA-Meter.

Technology keywords

Not reported

Other awards by this recipient

Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.

Research funding history

8 SBIR/STTR records share this UEI (2014–2025). Reported award amounts total $3,106,874. Reported amounts are not federal obligations.

Phases: Phase I, Phase II

Agencies: Department of Health and Human Services, Department of Agriculture, National Science Foundation

Agency intelligence

Department of Health and Human Services

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