Rapid, Field Deployable Alphavirus and Flavivirus Identification Assay

To provide improved disease surveillance capability, INT will develop assays for rapid identification of vectors carrying alpha, flavi or bunya viruses in the field. INT has developed a novel electronic nucleic acid sensor system, a universal automated sample preparation approach and a manufacturable, low cost disposable fluidic cartridge. The system features a unique nucleic acid-based diagnostic approach, which provides the capability for running diagnostic tests in the field. Tests can be run in minutes at remote locations where certain diseases are endemic. Together, these performance characteristics provide immediate results for better-informed preparation, treatment and disease management. Utilizing a multiplex microchip, the diagnostic system will provide the army capabilities for the rapid and accurate identification of alphavirus, flavivirus, or bunyaviruses from samples of infected insects.