SBIR/STTR Research Award
Malarial Vaccines Utilizing Antigen/Adjuvant Display on Viral-Like Particles
Award amount
$629,510Program and phase
SBIR · Phase IIAward year
2011Award details
- Awarding agency
- Department of Defense
- Branch
- Army
- Recipient company
- AGAVE BIOSYSTEMS INC.
- Proposal award date
- 2011-08-01
- Contract end date
- Not reported
- UEI
- SDSPMQR27BH4
- Solicitation number
- 2009.2
- Topic code
- A09-107
Research abstract
Recent studies have suggested the potential of improved malarial vaccines by use of the viral-like particle (VLP)-linked immunogen approach. The VLP technology is being utilized for the development of vaccines for a variety of diseases. Agave BioSystems is creating a novel platform for development of malarial vaccines consisting of a VLP displayed malarial antigen/adjuvant based on the Norwalk virus (NV) capsid protein. The VLP will be engineered to express a candidate antigen in combination with a peptide adjuvant. These VLPs will be characterized, purified and delivered for testing of efficacy to stimulate cellular and humoral immune responses.In the Phase I, Agave BioSystems successfully demonstrated proof-of concept for this novel platform.
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Novel Screen Approach to Inactivate Whole Viral Vaccines by Supralethal Irradiation
- Identification of Patients with Clostridium Difficile Infection, Colonization and/or Reoccurrence
- Intracellular Detection of Small Molecules in Live Cells
- Multiplex Immunoassays in the Development of Vaccines Against Enteric Pathogens
- Screens for Novel Agonists/Antagonists of Endocrine Fibroblast Growth Factors
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- GeMI-Vax as a multi-life stage malaria vaccine
- GeMI-Vax as a multi-life stage malaria vaccine
- Malarial Vaccines Utilizing Antigen/Adjuvant Display on Viral-Like Particles
Research funding history
102 SBIR/STTR records share this UEI (1998–2015). Reported award amounts total $29,837,745. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Defense, Department of Health and Human Services, National Aeronautics and Space Administration, Environmental Protection Agency