Miniature, Portable, Device to Detect and Monitor Coagulopathy

The objective of this proposal is to demonstrate the feasibility of a new thromboelastograph (TEG)-like instrument that has the same basic capabilities as the TEG – that is to say, capabilities of monitoring in vitro the kinetics, strength, and stability of clot formation in blood samples that are clot induced – but which is miniaturized, highly portable, rugged, and insensitive to adverse environmental conditions. Because current TEG devices use fundamental technology that is difficult to miniaturize and make robust, our approach will incorporate completely different technology and physical processes to measure comparable blood clotting parameters; it will furthermore provide various more advanced testing features.