SBIR/STTR Research Award

Improved Formulations to Enhance Bio-availability for Antisense Therapeutics

Award identifier e2e6ba516a99bc39a23dfdb90e8a72c40096938c178aec4b1e6e51a6ff1fc28bAwarding agency Department of Defense · Office for Chemical and Biological Defense

Award amount

$70,000

Program and phase

SBIR · Phase I

Award year

2010

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Award details

Awarding agency
Department of Defense
Branch
Office for Chemical and Biological Defense
Recipient company
LNKCHEMSOLUTIONS
Proposal award date
2010-05-17
Contract end date
2010-11-16
UEI
Not reported
Solicitation number
2010.1
Topic code
CBD10-102

Research abstract

In general, many biological and chemical agents affect the lungs directly or indirectly, even if the respiratory system is not the primary target organ of a military or terrorist attack. Both in the case of military and civilian attacks the lung can be one of the first organs affected by a chemical or biological agent. LNK Chemsolutions (LNK) with expertise in nanoparticle formulations and the University of Illinois Chicago with expertise in Acute Lung Injury (ALI) molecular biology and treatment modality development have teamed up to develop novel oral and inhalation formulation of targeted nanoparticles (NPs) containing siRNA and/or miRNA to improve the treatment of ALI unobtainable with current delivery systems.

Technology keywords

Not reported

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Agency intelligence

Department of Defense

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