A Non-invasive Brain Computer Interface to Remotely Monitor and Diagnose Warfighters at Risk for PTSD

Brain Computer Interface, LLC (BCI) proposes to investigate the feasibility of developing a non-invasive system (MindScope) to remotely monitor and diagnose warfighters at risk for PTSD. BCI will utilize wireless dry electrode electroencephalography (EEG) headsets communicating with laptop PC’s (later PDAs) running BCI software. Human Phase I study participants will perform BCI’s dynamic brain stimulation tests to generate data for analysis. In two independent studies, BCI will (i) record scans from healthy participants to confirm baseline reproducibility, and (ii) in collaboration with Sinai Hospital and the National Rehabilitation Hospital, assess feasibility to detect statistical differences in the power spectral density (PSD) metrics of PTSD patients, mTBI patients, and control participants. Established scientific literature has shown that EEG metrics can classify PTSD from healthy controls, but EEG technology has previously been too cumbersome to generate significant relevant data under dynamic brain stimulation conditions. BCI will leverage hardware advances and an extensive clinical data collection network to generate this data, and to innovate, analyze and apply it to create BCI’s MindScope mobile physiological testing system to assess brain health. Ultimately, the system will create personalized biometric brain signatures, allowing remote monitoring and diagnosis of brain status against baseline “normal” data.