SBIR/STTR Research Award
Development of a Simple and Rapid Assay for Field Detection of Dengue Viral RNA
Award amount
$68,072Program and phase
SBIR · Phase IAward year
2010Award details
- Awarding agency
- Department of Defense
- Branch
- Army
- Recipient company
- Biosearch Technologies, Inc
- Proposal award date
- 2010-02-22
- Contract end date
- 2010-09-21
- UEI
- NX7NLJUNSEU6
- Solicitation number
- 2009.3
- Topic code
- A09-155
Research abstract
Biosearch Technologies is a fluorescent oligonucleotide probe and assay development company which has been involved in recent government contracts for Biowatch 1 and 2, and in the production of infectious disease assays for the US Air Force. Biosearch is the only CDC-approved vendor for the 2009 HINI swine flu. For this Solicitation, Phase I will develop and provide a Point-of-Care (POC) assay for the four known serotypes of dengue virus. The assay will use an isothermal system called Recombinase Polymerase Amplification (RPA) which is capable of detecting down to one copy of virus target in 20 minutes at 37 degrees C. The instrumentation is stand-alone, and provides detection using field-deployable battery power. The assay reagents are dried and currently stable without refrigeration. Nasal swabs, buccal swabs, or small volumes of blood require no sample preparation, simply mix the sample and begin the amplification reaction. Detection is by direct fluorescence, and the instrument is capable of multiplexing.
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Development and Commercialization of Analyte Specific Reagents (ASRs) for the Diagnosis of Rickettsial Diseases on FDA-cleared Real-time PCR Platforms
- Development and Commercialization of Analyte Specific Reagents (ASRs) for the Diagnosis of Selected Arthropod-Borne Viruses on FDA-Cleared Real-time P
- Development and Commercialization of Analyte Specific Reagents (ASRs) for the Diagnosis of Rickettsial Diseases on FDA-cleared Real-time PCR Platforms
- Development and Commercialization of Analyte Specific Reagents (ASRs) for the Diagnosis of Selected Arthropod-Borne Viruses on FDA-Cleared Real-time P
- Azoreductase mediated fluorescence assays
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- A Point-of-Care Field Assay for Dengue Viruses
- A Point-of-Care Field Assay for Dengue Viruses
- Development of a Simple and Rapid Assay for Field Detection of Dengue Viral RNA
Research funding history
24 SBIR/STTR records share this UEI (1987–2010). Reported award amounts total $6,757,218. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Health and Human Services, Department of Defense