Non Invasive Assessment of Intracranial Pressure and Cerebrovascular Status after Traumatic Brain Injury

Intracranial pressure, ICP, is arguably the single most important parameter used clinically to manage brain injury and long-term brain damage. Existing methods to record ICP are either invasive or require large equipment incompatible with a field deployable system. Our work combines two highly promising methods for monitoring ICP into a compact unit capable of continuous monitor. Using this bimodal approach will result in a single device that will lead to the definitive non-invasive device for monitoring ICP in far-field use. Our device incorporates retinal venous doppler ultrasonography (RVD) and pressure pulsatility analysis (PPA) into a single, compact unit safe for continuous automated use. We present innovations in PPA that enable continuous monitoring with more accurate readings from the RVD. Our device will enable monitoring of ICP on all patients with suspected brain injury, which will benefit the military as well as civilian health providers, from EMTs and paramedics to nurses and doctors in central hospitals.