SBIR/STTR Research Award

Biomarkers for Occult Neural Infectious Disease

Award identifier 3d61cfe490e81f42ff0af93d45d2f44c17f51db7bb20539df2c82b1333a10a1cAwarding agency Department of Defense · Air Force

Award amount

$99,996

Program and phase

SBIR · Phase I

Award year

2009

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Award details

Awarding agency
Department of Defense
Branch
Air Force
Recipient company
PROTEIN EXPRESS, INC.
Proposal award date
2009-02-19
Contract end date
2009-08-19
UEI
Not reported
Solicitation number
2008.2
Topic code
OSD08-H05

Research abstract

Despite years of research, the etiology of senile dementia of the Alzheimer’s type (AD) is still unknown. Infectious agents have never been ruled out, and our reliminary studies suggest that bacteria derived from AD brain slices cultured in our novel EBTKS medium may be involved. To identify these bacteria, brain slices will be cultured and non-human DNA sequences derived from the culture by massively parallel means. These sequences will permit (1) the determination of diagnostic PCR primer sets and (2) antigenic peptides that may be used to develop antibody-based diagnostic reagents.

Technology keywords

Not reported

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Agency intelligence

Department of Defense

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