Bioinformatic Based Wearable Critical Care Monitor

The objective of this Phase I application is the focused development of an advanced bioinformatic based wearable critical care monitor to enhance warfighter medical care. This will be accomplished by building upon an existing advanced sensor, hardware and software platform developed by BodyMedia Advanced Development combined with additional computational and clinical expertise provided by Virginia Commonwealth University (VCU). The effort will utilize advanced computational techniques allowing for data fusion of easily obtained low level signals to derive meaningful physiologic outputs. In this application we will harness our current capability to record galvanic skin response, temperature, heat flux, and heart rate to produce usable values of blood pressure, pulse pressure, oxygen consumption, oxygen debt, and heart rate related changes in volume loss. Physiologic data for the initial level of computational development will be obtained through an existing relationship between VCU and the US Army Institute of Surgical Research using models of lower body negative pressure. The device will provide contextual information such as level of activity to the analysis of physiologic signals thus making their interpretation more useful. Such a device should enable remote triage as well assisting in the point of care diagnosis and treatment of the wounded warfighter.