Non-invasive monitoring of intracranial pressure

Intracranial pressure, ICP, is arguably the single most important parameter used clinically to manage brain injury and long-term brain damage. Existing methods to record ICP are invasive, however, either going through the skull or into a brain ventricle. Many researchers are currently exploring methods for monitoring ICP through non-invasive means. Our work combines two highly promising methods, both backed by clinical research performed by our teaming partners, and combine them into a single device that will lead to the definitive non-invasive device for monitoring ICP in far-field use. Our device incorporates ophthalmodynamometry and arterial phase lag monitoring into a single, compact unit safe for continuous automated use. We present innovations in ophthalmodynamometry that enable this leap to continuous use as well as image analysis that can rapidly analyze the retinal images and data integration to provide feedback from multiple sensors. Our device will enable monitoring of ICP on all patients with suspected brain injury, which will benefit the military as well as civilian health providers, from EMTs and paramedics to nurses and doctors in central hospitals.