Deployable Intracranial Sensor Array

Cortical Spreading Depression (CSD) as a secondary phenomenon to traumatic head injury can herald further brain tissue damage well after the initial injury. The only way to reliably record CSD is through direct electrode contact with the brain. With modern equipment this requires that the skull and dura be removed, which is only feasible in a small number of patients. Infoscitex and our partners at Children’s Hospital Boston propose a novel subdural electrode array capable of being inserted through a standard hole used for intra-cranial pressure (ICP) monitoring. One of our arrays alone can cover 6 cm2 of cortical tissue, and has electrodes spaced up to 1 cm apart. The design of our array is ideal for recording the low-frequency waves of CSD. Our array will be beneficial in cases both of traumatic head injury and also brain injuries from stroke. The potential benefits to monitoring for CSD in all patients who require ICP monitoring is vast, due to the number of potential patients and the high incidence of secondary injury. The team assembled for this program involves experts in the field of subdural electrode placement and signal recording, as well as considerable experience in developing minimally invasive medical devices.