COMBINATORIAL SYNTHESIS OF HIV1 INTEGRASE INHIBITORS

Not Available Active imaging in the short- and mid-wave infrared has well-known benefits versus shorter wavelengths: eye safety, better visibility through battlefield obscurants, high atmospheric. transmission, and reduced background emission. However, detectors in this spectral region suffer from low bandwidths and poor sensitivity, often requiring cryogenic cooling to achieve a modest detectivity. CTI proposes to enhance the active imaging capability in the 1.5 to 4 -um region by utilizing a nonlinear optical (NLO) converter which provides frequency shifting to shorter wavelengths where cheaper, faster, lower noise, and room-temperature detectors exist. In addition, it provides optical gain, spectral filtering, controlled field-of-view, and superior rejection of background radiation. This results in an increase in performance to nearly the shot-noise limit without sacrificing ranging capability. Modern NLO materials can operate with high efficiency using modest pump sources in a compact design. The enhanced receiver capability reduces the pump power constraints resulting in a more compact overall system. Advanced sensor functionality including range-gating can be performed optically by modulating the pump source. In Phase I, CTI will conduct detailed analyses and laboratory demonstrations to validate the proposed concept. In Phase II, an enhanced-imaging breadboard receiver will be tested and delivered.