A PORTABLE MICROPROCESSOR-BASED MEMORY AID WILL BE DEVELOPED FOR PATIENTS WITH ORGANIC MEMORY IMPAIRMENTS AFFECTING THEIR ABILITY TO REMEMBER INTENTIONS (SUCH AS TASKS OR APPOINTMENTS).

A PORTABLE MICROPROCESSOR-BASED MEMORY AID WILL BE DEVELOPED FOR PATIENTS WITH ORGANIC MEMORY IMPAIRMENTS AFFECTING THEIR ABILITY TO REMEMBER INTENTIONS (SUCH AS TASKS OR APPOINTMENTS). IN PHASE I OF THIS PROJECT, MODIFICATIONS WILL BE MADE TO AN INEXPENSIVE, COMMERCIALLY AVAILABLE POCKET COMPUTER, AND SOFTWARE WILL BE DEVELOPED COGNITIVELY IMPAIRED INDIVIDUALS. A SMALL STUDY OF THE UTILITY OF THE MEMORY AID DEVICE WILL BE CONDUCTED WITH A GROUP OF 12 TRAUMATICALLY HEAD-INJURED SUBJECTS WITH ANTEROGRADE AMNESIA. MEASURES WILL INCLUDE PATTERNS OF USE OVER TIME, ELECTED DURATION OF USE, AND RATED UTILITY. THIS APPLICATION OF MICROPROCESSOR TECHNOLOGY IS EXPECTED TO PROVIDE AN ELECTRONIC PROSTHESIS FOR IMPAIRED MEMORY. PHASE II OF THE PROJECT WILL PRODUCE FURTHER HARDWARE REFINEMENTS (INCLUDING MINIATURIZATION FOR IMPROVED PORTABILITY) AND WILL ELUCIDATE SUBJECT VARIABLES WHICH INFLUENCE USE IN PROSPECTIVE PATIENT POPULATIONS. COMMERCIAL APPLICATIONS ARE ENVISIONED IN THE DEVELOPMENT OF AN EFFECTIVE THERAPEUTIC AID FOR A VARIETY OF ORGANICALLY