SUPERCRITICAL FLUID EXTRACTION AND ANALYSIS OF RESIDUES IN MEATS

ANALYTICAL METHODS FOR DETECTING PESTICIDES, ANTIBOIOTICS, AND METABOLIC PRODUCTS IN MEAT PRODUCTS ARE TEDIOUS AND TIME-CONSUMING. THIS STUDY WILL EVALUATE SUPERCRITICAL FLUID EXTRACTION AND CHROMATOGRAPHIC TECHNIQUES FOR ANALYSIS OF THESE COMPOUNDS WHICH MAY BE POLAR, THERMALLY UNSTABLE, OR OTHERWISE INTRACTABLE TO OTHER METHODS. IN PHASE I, WE WILL DEMONSTRATE ANALYSIS OF RESIDUES BY SFC; DEMONSTRATE SUPERCRITICAL FLUID SOLUBILITY EFFECTS, AND EVALUATE SFC DETECTORS. SUBSEQUENT PHASES WILL DEVELOP IMPROVED DETED DETECTION AND PUMPING SYSTEMS AND NEW CAPILLARY COLUMN COATINGS OPTIMIZED FOR SPECIFIC ASSAYS OF INTEREST TO THE USDA.