Use of Low-Energy Electromagnetic Fields (EMFs) to Advance Tissue Regeneration

The project goal is to advance use of low-energy electromagnetic fields (EMFs)to target specific biological pathways associated with limb regeneration for the purpose of replacing lost limbs in humans due to military injuries. A tadpole regeneration modelwill be used to decipher biologically active molecules corresponding to loss of regeneration potential as a tadpole matures. These factors will be targeted using multiple modalities such as proteins, gene therapy, and EMFs with the intention of forming ablastema-like state in human cells. Collaborators include Indiana University, University of Illinois, and California Institute of Technology.