SBIR/STTR Research Award

Quantitative Genome Based Method for Detecting Viruses

Award identifier cc381dd0a2af6b23a221b3e4847fed034366a98f4f3de44014826170461113cfAwarding agency Department of Health and Human Services

Award amount

$80,327

Program and phase

SBIR · Phase I

Award year

1995

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Award details

Awarding agency
Department of Health and Human Services
Branch
Not reported
Recipient company
SYMBIOTECH, INC.
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

Advances in the field of in vitro diagnostics (IVDs) have reduced the levels of hepatitis B & C inQuantitative, genome-based IVDs for-hepatitis are being developed using the polymerase chain reactioThese lVDs are more sensitive than the currently employed IVDs; therefore, they have the potential tlevels of contaminated blood. In addition, quantitative IVDs are needed to monitor treatments and totreatments for viral infections. The primary concerns among clinicians regarding the PCR technologysusceptibility to contaminating DNA and the lack of standardization. Both of these problems are inhetechnology, which involves amplifying a few DNA molecules to several million copies. The long term oresearch is to develop quantitative, genomic-based IVDs for a range of infectious viruses and bacterproprietary technology which does not involve DNA amplification. The presence of viral DNA or RNA afof a probe. The method has the potential to be more sensitive than PCR because release of a single pAn automated version of the method will be developed in a 96 well format.

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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