SBIR/STTR Research Award
Quantitative Genome Based Method for Detecting Viruses
Award amount
$80,327Program and phase
SBIR · Phase IAward year
1995Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- SYMBIOTECH, INC.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
Advances in the field of in vitro diagnostics (IVDs) have reduced the levels of hepatitis B & C inQuantitative, genome-based IVDs for-hepatitis are being developed using the polymerase chain reactioThese lVDs are more sensitive than the currently employed IVDs; therefore, they have the potential tlevels of contaminated blood. In addition, quantitative IVDs are needed to monitor treatments and totreatments for viral infections. The primary concerns among clinicians regarding the PCR technologysusceptibility to contaminating DNA and the lack of standardization. Both of these problems are inhetechnology, which involves amplifying a few DNA molecules to several million copies. The long term oresearch is to develop quantitative, genomic-based IVDs for a range of infectious viruses and bacterproprietary technology which does not involve DNA amplification. The presence of viral DNA or RNA afof a probe. The method has the potential to be more sensitive than PCR because release of a single pAn automated version of the method will be developed in a 96 well format.
Technology keywords
Not reported