Automated Daily Dose Reconstruction and Delivery Verification for External Beam Radiotherapy

? DESCRIPTION (provided by applicant): Abstract Approximately half of the 1.6 million people diagnosed with cancer in 2013 in the United States will receive radiation therapy in the management of their disease. Because each course of radiation therapy is tailored to the disease and anatomy of the patient, delivery of the intended dose is dependent upon, in part, the ability of the treatment machine to reproduce the planned treatment parameters. Despite this, the current quality assurance paradigmin radiation oncology does not provide independent verification that the plan has been correctly delivery each time the patient has been treated. Indeed, current practice is largely dependent upon internal safeguards deployed by the linear accelerator manufacturer to recognize meaningful system deviations and terminate delivery accordingly. The motivation for this application is an urgent need for commercial tools that improve confidence in daily treatment of every radiation therapy patient. The overarching