SBIR/STTR Research Award

Resorbable Tubular Collagen Implant--Endoscopic Repair

Award identifier 6fe8729a70d603714783f4589ed4c489130d7133d86644793a24eab637bfd8f8Awarding agency Department of Health and Human Services

Award amount

$98,646

Program and phase

SBIR · Phase I

Award year

1995

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Award details

Awarding agency
Department of Health and Human Services
Branch
Not reported
Recipient company
COLLAGEN MATRIX, INC.
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

Urethral strictures have long been a therapeutic dilemma for urologists. The natural course of theprogressive scarring and narrowing of the urethral lumen. Multiple attempts at developing and optimshort of an adequate cure rate. Often the procedures have resulted in an increased progression of tstricture rather than resolving the disease. Presently, internal urethrotomy is the primary surgicamost minor and moderate strictures. It has been demonstrated that this procedure, which relies on hintention, is more a managerial rather than a curative therapy. The use of an endoscopically placedbioresorbable tubular collagen implant to seal the incised areas and provide an enlarged conduct aftoffers a potential cure for urethral strictures. The tubular collagen implant functions as a biomecbiological dressing to the wound bed. The collagen matrix acts as a substrate for the migration ofscaffold for new tissue regeneration. This tubular collagen implant can also be used as a deliveryand cultured epithelial cells to further enhance healing and prevent scar formation.

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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