SBIR/STTR Research Award
Resorbable Tubular Collagen Implant--Endoscopic Repair
Award amount
$98,646Program and phase
SBIR · Phase IAward year
1995Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- COLLAGEN MATRIX, INC.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
Urethral strictures have long been a therapeutic dilemma for urologists. The natural course of theprogressive scarring and narrowing of the urethral lumen. Multiple attempts at developing and optimshort of an adequate cure rate. Often the procedures have resulted in an increased progression of tstricture rather than resolving the disease. Presently, internal urethrotomy is the primary surgicamost minor and moderate strictures. It has been demonstrated that this procedure, which relies on hintention, is more a managerial rather than a curative therapy. The use of an endoscopically placedbioresorbable tubular collagen implant to seal the incised areas and provide an enlarged conduct aftoffers a potential cure for urethral strictures. The tubular collagen implant functions as a biomecbiological dressing to the wound bed. The collagen matrix acts as a substrate for the migration ofscaffold for new tissue regeneration. This tubular collagen implant can also be used as a deliveryand cultured epithelial cells to further enhance healing and prevent scar formation.
Technology keywords
Not reported