THE PLASMA PROTEINS REPRESENT THE MOST THOROUGHLY CATALOGUEDGROUP OF HUMAN PROTEINS.

THE PLASMA PROTEINS REPRESENT THE MOST THOROUGHLY CATALOGUEDGROUP OF HUMAN PROTEINS. HIGH-RESOLUTION, TWO-DIMENSIONAL ELECTROPHORESIS HAS ALLOWED THE CONSTRUCTION OF COMPREHEN- SIVE MAPS OF THE PLASMA PROTEINS AND MAKES POSSIBLE THE CONSTRUCTION OF A PROTEIN INDEX DATABASE COVERING THEIR MOLECULAR AND OTHER PROPERTIES. RESEARCHERS HAVE IDENTIFIED40 POLYPEPTIDE COMPONENTS ON THE PLASMA PROTEIN MAP, LEAVINGPERHAPS 100 PROTEINS DETECTED BUT UNIDENTIFIED. THIS PROJECT CONCERNS AN EFFORT TO IDENTIFY AS MANY OF THE REMAINING KNOWN PROTEINS AS POSSIBLE AND TO BEGIN COLLECTIONOF PERTINENT MOLECULAR DATA FOR EACH PROTEIN IN ORDER TO CREATE A USEFUL HUMAN PLASMA PROTEIN INDEX. BOTH EXPERIMENTALLY-DERIVED AND LITERATURE-DERIVED DATA WILL BE INCLUDED. IN PHASE II, THIS DATABASE WILL BE MADE AVAILABLEON LINE TO RESEARCHERS CONCERNED WITH PLASMA PROTEIN ANALYSIS.