SBIR/STTR Research Award
HIGH RESOLUTION X-RAY FLUORESCENCE DETECTOR
Award amount
$100,822Program and phase
SBIR · Phase IAward year
2001Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- HD TECHNOLOGIES, INC.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
DESCRIPTION (Verbatim from the Applicant's Abstract): It has been demonstrated
that multilayer analyzer array detector is advantageous in x-ray fluorescence
detection under high flux and dilute metal conditions. With a good rejection
rate, about 25 times, and reasonably large solid angle, sub-millimolar
concentration can be routinely accessed. However, the performance of the
detector is still lagging behind the photon flux and brightness increases at
the third or even fourth generation synchrotron sources. With more than 100 to
1000 flux increases at the third generation source, these sources would permit
detection of metal concentration in the order of 10 micro-Molar or several ppm
range. This will allow the monitoring of some biologically relevant metals in
vivo. Thus we propose to develop x-ray fluorescence detector using synthetic
multilayer pairs. With two-stage rejection of primary and secondary
multilayers, it is anticipated that the rejection rate will exceed 200 times.
With a 20 percent throughput, the anticipated gain on the effective count rate
can be as high as 40 times on dilute systems. Initial evaluation shows that the
detector can be made tunable in a wide energy region and to cover a large solid
angle. The major goal for the Phase I project is to design and fabricate a
prototype multilayer pair detector. The test and evaluation of the detector
performance will aid in the design of a multilayer pair analyzer array
detector. Phase II project will develop such a detector to a product.
PROPOSED COMMERCIAL APPLICATION:
The need for a very sensitive and high count rate x-ray fluorescence detector is well
justified. The instrument will be vital to x-ray spectroscopy and micro fluorescence
imaging on biological systems under high flux and dilute situations. With ever increasing
photon flux at the new synchrotron sources, the detector will have a better market
potential than fluorescence ionization chambers and the solid state detectors which are
currently available.
Technology keywords
Not reported