SBIR/STTR Research Award

Not Available

Award identifier 52abeb3cf9316e85787a8394485b5d518291b59bcde94731ae643b179279b420Awarding agency Department of Health and Human Services · National Institutes of Health

Award amount

$207,803

Program and phase

SBIR · Phase I

Award year

2010

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Award details

Awarding agency
Department of Health and Human Services
Branch
National Institutes of Health
Recipient company
VM DISCOVERY, INC.
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
PHS2010-1
Topic code
NCI

Research abstract

Breast cancer is a devastating affliction in Western Society. It is of high interest to quantify the expression of HER2/neu (a growth factor receptor), the estrogen receptor (ER), and the progesterone receptor (PR) in breast cancer tumors since HER2/neu expression is associated with high malignancy and because HER2Ineu, and ER are targets for anti-breast cancer therapies (Herceptin and tamoxifen, respectively). The presence or absence of PR is also helpful in diagnosing the sensitivity of a tumor to tamoxifen, since PR expression is dependent upon ER activity. The assay will quantify the populations of cells expressing HER2/neu, ER, and PR in the tumor sections obtained from biopsy material or surgical resection

Technology keywords

Not reported

Awards with the same topic code

Verified by an exact topic code match. This is not a text-similarity match.

Agency intelligence

Department of Health and Human Services

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