Tangential Refractive Ablation at 193m

Photorefractive Keratectomy using a 193 nm wavelength excimer laser directed into the cornea is expapproved by the FDA in 1995. These systems are expected to cost approximately $450,000 due to the cocontrolling the laser beam and the mechanical iris. The York laser mirror system reflects a 193 nm ea hollow hemisphere over the cornea. A less sophisticated laser control system can be used resultingestimated 50% less. In Phase I a prototype York laser mirror system will be constructed. Feasibilityablating test eyes and explanted animal eyes microscopically and histologically. Upon successfully cPhase II study will integrate the prototype York laser mirror system with an excimer laser and contrintegrated system will then be used to ablate a series of animals to evaluate the healing process. Ucompletion, an IDE submission will be made to begin Phase I clinical trials in non- functional humanby the FDA, the York laser system will become a less expensive alternative for Photorefractive Keratsignificantly cutting the cost of the system more ophthalmologists will be able to afford the equipmprocedure. Third world countries will also be able to use the procedure to provide basic refractivepopulations. An estimated $125 million will be spent on refractive laser equipment by 1998. A 50% recost could result in a health care savings of $60 million per year.