MDI Commercial Actuator Chronolog

Metered dose inhalers are integral to the treatment of Asthma. Poor compliance to regimens and inapusage of pm medications has been documented in the literature as a serious problem. Data submitted tpharmaceutical companies are questionable without compliance data. Previous MDI chronolog devices haquestionable drug delivery concerns. We will develop a system to remotely monitor usage of all MDI minterference. Significant features of the MDICAC will be (1) attach to any commercial MDI actuator wto drug delivery, (2) record the time of dispensing from any commercial actuator, (3) sense the patiaudibly remind the patient for dispensings, (5) provide visual information to the patient, (6) storeactuations, (7) provide canister dosage count, (7) bi-directional transfer of instructions and inforlocation with a personal computer database system, (8) low cost. Significant, measurable benefits tomanufacturing companies engaged in clinical trials for proof of safety and efficacy and the primaryin the managed treatment of the chronically ill will be established through studies performed in Pha