SBIR/STTR Research Award
Photoacoustic CT for Preclinical Molecular Imaging
Award amount
$2,997,250Program and phase
SBIR · Phase IIAward year
2009Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- OPTOSONICS, INC.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- PHS2009-2
- Topic code
- Not reported
Research abstract
DESCRIPTION (provided by applicant): The long-term objective of this collaborative research project is to commercialize a prototype photoacoustic computed-tomography (PCT) scanner for conducting preclinical molecular imaging. This scanner has been developed by OptoSonics with funding from a Fast Track SBIR grant from the National Cancer Institute (R44-CA-102891) and additional private funding from our Endra, Inc. Researchers at Indiana University, Purdue University and OptoSonics evaluated this device in a number of murine models of cancer and developed quantitative techniques to measure hemoglobin concentration, oxygen saturation and accumulation of exogenous molecular probes in tissue in three dimensions with spatial resolution lt 350 m. This Bridge grant will supplement additional financing from Endra for continued product development, including instrumentation and software features to be validated in animal models of cancer.
Technology keywords
Not reported