NEW CONJUGATE VACCINE FOR GRAM NEGATIVE SEPSIS

Not Available Technology required to creat a pulsed detonation engine (PDE) has been maturing rapidly inthe recent past. The airbreathing and rocket modes of operation of such a device can potentially b combined to result ina performance leader for long range, low cost and high mach number propulsion needs. As such, the efficiency of PDEs is augmented by the flesibility offered by the multi-mode operation. In this proposal HyPerComp, a small business and leader inthe development and application of computational technologies to aerospace engineering problems, together with the University of Texas a Arlington and Lockheed-Martin Tactical Aircraft systems in Fort Worth, proposes to validate an innovative design based on these concepts. This team has well established and internationally reowned strengths in the areas of aerodynamics, airframe integration, design and simulation of pulse detonation devices. it has a capability to conduct large scale computatios of fluid mechanics problems with finite rate chemistry includig detonation. Individual team members have extensive experience inthe area of pulse detonation both from analytical and epxerimental perspectives, have numerous publications and patents directly concerning pulsed detonationand are ideally suited to undertake research to further the frontiers in this area.