SBIR/STTR Research Award
High-Throughput System for Protease Activity Profiling
Award amount
$2,118,754Program and phase
SBIR · Phase IIAward year
2011Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- PROGNOSYS BIOSCIENCES, INC.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- PA10-050
- Topic code
- NIGMS
Research abstract
DESCRIPTION (provided by applicant): There is a need for new technologies to enable the analysis of the proteome. We propose to develop a novel technology for analyzing protease activity. Proteases are involved in the regulation of essential cellular processes and misregulation of proteolytic activity is involved in many diseases such as neurodegeneration, cardiovascular diseases, arthritis, Alzheimer's disease, cancer, and infectious diseases. PUBLIC HEALTH RELEVANCE: The protease activity profilingtechnology we are developing is useful for identifying new protease drug targets for drug development. It would help to elucidate the functional roles of specific proteases and may result in advances in the diagnosis and treatment of disease.
Technology keywords
Not reported
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