THE ULTIMATE GOAL OF THIS PROJECT IS TO DEVELOP A METHOD FORCARRYING OUT URODYNAMIC BEHAVIOR TESTS BASED ON CONTINUAL MONITORING OVER A PROLONGED PERIOD OF TIME THAT INCLUDES ROUTINE DAILY ACTIVITIES.

THE ULTIMATE GOAL OF THIS PROJECT IS TO DEVELOP A METHOD FORCARRYING OUT URODYNAMIC BEHAVIOR TESTS BASED ON CONTINUAL MONITORING OVER A PROLONGED PERIOD OF TIME THAT INCLUDES ROUTINE DAILY ACTIVITIES. THE SPECIFIC AIMS ARE TO DEVELOP A PORTABLE MONITORING SYSTEM ATTACHED TO THE PATIENT THAT CAN RECORD PHYSIOLOGICAL DATA OVER A 24-HOUR PERIOD AND TO IMPLEMENT AUTOMATED METHODS FOR ANALYZING THE RECORDED DATA.THIS APPROACH WILL RESULT IN A SYSTEM THAT WILL ALLOW DYNAMIC INFORMATION TO BE INCORPORATED INTO A PATIENT'S UROLOGIC HISTORY AND WILL ASSIST THE CLINICIAN IN ESTABLISH-ING DIAGNOSTIC AND TREATMENT PROCEDURES. PHASE I WILL USE CONVENTIONAL EQUIPMENT TO TEST THE EFFICACY OF LONG-TERM URODYNAMIC MONITORING IN A POPULATION OF SPINAL CORD INJURIES; THIS WILL INCLUDE PRELIMINARY MANUAL INTERPRETA- TION OF THE DATA. THE TESTS WILL BE CARRIED OUT DURING RESTING CONDITIONS SIMILAR TO ROUTINE STUDIES, AND DURING DYNAMIC CONDITIONS THAT INCLUDE VARIOUS DAILY FUNCTIONAL TASKS. THE RESULTS OF PHASE I WILL BE USED IN PHASE II TO CONSTRUCT PORTABLE URODYNAMIC MONITORING EQUIPMENT AND AUTO-MATED SIGNAL PROCESSING ALGORITHMS. THESE WILL BE EVALUATEDIN DIVERSE PATIENT POPULATIONS BY MEANS OF A FORMAL ASSESSMENT PROTOCOL. THE TECHNOLOGICAL INNOVATION AND COMMERCIAL POTENTIAL OF THIS RESEARCH LIES IN THE DEVELOP- MENT OF A MARKETABLE PORTABLE URODYNAMIC MONITORING SYSTEM AND THE ESTABLISHMENT OF SCANNING CENTERS THAT WILL INTERPRET DATA AND FURNISH LABORATORY REPORTS.