CHEMICAL INTELLIGENCE FOR AUTOMATED SYSTEMS: CHEMILUMINESCENT ENZYME IMMUNO ASSAY DEVICE FOR TOXINS

A FEASIBILITY DEMONSTRATION PLAN IS PROPOSED FOR THE AFFINITY IMMOBILIZATION OF NON-CONSUMMABLE COMPONENTS OF A HOMOGENEOUS ENZYME IMMUNOASSAY SYSTEM, IN A FUNCTIONAL ARRANGEMENT WITH ONE ANOTHER ON A SILICA-BASED SENSOR SURFACE. THE BIOMEMBRANE CHEMICAL SENSOR DEVICE TO BE DEVELOPED THEREFROM, IS EXPECTED TO BE A FIELDABLE (SMALL AND RUGGED WITH LOW POWER AND CONSUMMABLE MATERIAL REQUIREMENTS) MULTI-ANALYTE CBT MICROSENSOR PROVIDING SPECIFIC, SENSITIVE AND CONTINUOUS (REAL-TIME) MONITORING FOR AT LEAST 24 HOURS WITHOUT MAINTENANCE. THE BIOACTIVE MEMBRANE COMPONENTS WILL BE READILY REPLACEABLE. THE DEVICE WILL REVERSIBLY RECOGNIZE AND TRANSDUCE THE AGENT BINDING EVENT WITH CAPABILITY FOR BOTH VISUAL AND ELECTRONIC RECORDING AND TRANSMISSION OF SIGNAL DATA.