SBIR/STTR Research Award

NEW FLUORINATED MRI PROBES FOR CELL IMAGING

Award identifier 2283275656a9d67e99c8ddf510300659ee669b345352adeacbf51284329641baAwarding agency Department of Health and Human Services · National Institutes of Health

Award amount

$117,497

Program and phase

SBIR · Phase I

Award year

2002

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Award details

Awarding agency
Department of Health and Human Services
Branch
National Institutes of Health
Recipient company
CARBOMER, INC.
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

DESCRIPTION (provided by applicant):New bio compatible probes are proposed for magnetic resonance imaging (MRI). 19F based probes will be prepared that are more suitable than existing products for rapid and sensitive oxygen mapping using 19F MRI. These probes will be employed to assess in a model system the viability, metabolic rate and oxygen consumption rates of rat INS-1 cells as surrogates of human is lets for potential applications in diabetes therapy. Preliminary data from pilot studies indicate that these new probes are promising and constitute a viable approach for improved cell viability control.

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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