LITERATURE IN THE AREA OF CHEMOPREVENTION THE LONG-TERM OBJECTIVE IS TO COMPILE A LIST OF THE MAJOR COMPOUNDS WHICH HAVE BEEN IDENTIFIED AS HAVING CHEMOPREVENTIVE ACTIVITY IN HUMANS AND ANIMALS.

LITERATURE IN THE AREA OF CHEMOPREVENTION THE LONG-TERM OBJECTIVE IS TO COMPILE A LIST OF THE MAJOR COMPOUNDS WHICH HAVE BEEN IDENTIFIED AS HAVING CHEMOPREVENTIVE ACTIVITY IN HUMANS AND ANIMALS. THE MAJOR ONLINE DATABASES IN MEDICINE, BIOLOGY, TOXICOLOGY AND PHARMACEUTICALS WILL BE SEARCHED TO IDENTIFY THE KEY INFORMATION RESOURCES ON CHEMOPREVENTION. A DATABASE OF THE CHEMOPREVENTIVE COMPOUNDS WILL BE MAINTAINED ON A MICROCOMPUTER. THE METHODOLOGY FOR PRIORITIZING A MASTER LIST OF THESE CHEMOPREVENTIVE COMPOUNDS, ACCORDING TO EFFICACY, TOXICITY, AND OTHER FACTORS WILL BE DEVELOPED. A COMPILATION OF ALL THE REVIEW ARTICLES A PRELIMINARY LIST OF ALL CHEMOPREVENTIVE COMPOUNDS DISCUSSED IN THE REVIEW ARTICLES A METHODOLOGY WHICH CAN BE USED TO OBTAIN, CHARACTERIZE A METHODOLOGY FOR COMPILING A PRIORITIZED MASTER THE RESULTS OBTAINED IN PHASE I WILL BE USED TO CONDUCT PHASE II RESEARCH. IN PHASE III, THE PUBLICATION, BY THE PRIVATE SECTOR, OF A HANDBOOK OF CHEMOPREVENTIVE COMPOUNDS WITH FREQUENT UPDATES WILL BE CONSIDERED. IN ADDITION, THE VIABILITY OF A SPECIALIZED DATABASE ON CHEMOPRE-VENTIVE COMPOUNDS WILL BE DETERMINED.