SMALL SIZED, CONTINUOUS MONITORING PIEZOELECTRIC CRYSTAL OR SAW DETECTORS WILL BE DEVELOPED FOR DETECTION OF COF OF CONTRABAND DRUGS USING IMMOBILIZED ANTIBODIES.

SMALL SIZED, CONTINUOUS MONITORING PIEZOELECTRIC CRYSTAL OR SAW DETECTORS WILL BE DEVELOPED FOR DETECTION OF COF OF CONTRABAND DRUGS USING IMMOBILIZED ANTIBODIES. MONITORS WILL BE DESIGNED THAT ARE (1) SPECIFIC FOR ONE DRUG AND (2) GENERAL DETECTORS FOR ANY OF SEVERAL DRUGS THAT MIGHT BE PRESENT. MONITORS WILL BE DESIGNED THAT ARE SIMPLE TO USE, OF LOW COST, AND ARE BASED ON ANALYTICAL METHODOLOGY OF SUITABLE ACCURACY, SENSITIVITY AND REPRODUCIBILITY. THESE MONITORS WILL BE THE SIZE OF A SMALL CALCULATOR WITH ALARM AND ALL-CLEAR FUNCTIONS, AND BE CAPABLE OF OPERATION AS CONTINUOUS ANALYZERS. THE INITIAL EVALUATION IN PHASE I WILL BE DONE USING COMMON DRUGS (COCAINE, HEROIN, MARUJANA, SPEED, PHENOBARBITAL-TWO OR PERHAPS THREE OF THESE, OR OTHER DRUGS OF INTEREST, WILL BE CHOSEN FOR STUDY TO ASCERTAIN THE UTILITY OF THE CONCEPT FOR VARIOUS APPLICATIONS. THE PROTOTYPE MONITORS WILL BE EVALUATED FOR LIFETIME, RESPONSE, ETC.