SBIR/STTR Research Award

Hare--A Polynomial Spleen Survival Analysis Module

Award identifier 8c6e63d004dd7d38dcd1b2af1fcf69f1ed1838077ec9f7803dfd34ae1c3a0b29Awarding agency Department of Health and Human Services

Award amount

$89,982

Program and phase

SBIR · Phase I

Award year

1995

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Award details

Awarding agency
Department of Health and Human Services
Branch
Not reported
Recipient company
INSIGHTFUL CORPORATION
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

Survival analysis methods are widely used in medical research: in clinical trials, in pharmacologicstudying the effects of ionizing radiation, in screening for breast and colon rectal cancer, and intransmitted diseases. There has been considerable interest in the biostatistics literature regardingestimate the log-hazard function. We will incorporate recent and ongoing advances in this area intospline survival analysis module to be integrated into S-Plus, a modern statistical analysis system.times are generated by some unknown mechanism, interest often lies in estimating a hazard, survival,HARE these functions will be estimated by means of polynomial splines and their selected tensor prodbivariate survival models with covariates. HARE will also compute standard and not--so-- standard tegraphical display of the resulting estimates and diagnostics will be comprehensive. An algorithm empaddition and deletion of basis functions makes adaptive survival function estimation possible in HARcan be (and will be) applied to other models such as multiple logistic regression and classification

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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