SBIR/STTR Research Award
Novel CSF biomarker to predict impaired cognition in HIV
Award amount
$0Program and phase
STTR · Phase IAward year
2004Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- INFLAME THERAPEUTICS, INC.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
DESCRIPTION (provided by applicant): The focus of this project is to explore the relationship between inflammatory cells and cognitive dysfunction in populations with HIV-1 infection. Extensive work has found that a biomarker is detected in lumbar cerebrospinal fluid of HIV(+) subjects with impaired cognition. Presently there are no suitable clinical tests to identify early neuro-inflammatory injury to neurons in such disorders as HIV-1 dementia. The ability to identify and treat HIV(+) populations before the onset of irreversible brain damage is highly desirable and forms the basis for this STTR proposal.
Technology keywords
Not reported