SBIR/STTR Research Award

AIT-082; A DRUG FOR TREATMENT OF ALZHEIMER'S DISEASE

Award identifier 83ba10c7eb9d40f0a7ff2edc523d7e39554ec3374df214f41e61fc48b25c862eAwarding agency Department of Health and Human Services

Award amount

$478,811

Program and phase

SBIR · Phase II

Award year

1993

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Award details

Awarding agency
Department of Health and Human Services
Branch
Not reported
Recipient company
Advanced Immunotherapeutics
Proposal award date
Not reported
Contract end date
Not reported
UEI
Not reported
Solicitation number
Not reported
Topic code
Not reported

Research abstract

WE WILL DEVELOP AIT-082 FOR THE TREATMENT OF DEMENTIA DUE TO ALZHEIMER'S DISEASE, STROKE OR AGING. IN PHASE I, WE PLAN TO COMPLETE THE PRECLINICAL STUDIES NEEDED TO SUBMIT AN INVESTIGATION- AL NEW DRUG (IND) EXEMPTION APPLICATION TO THE FOOD AND DRUG ADMINISTRATION (FDA). SPECIFICALLY, WE WILL: (1) DETERMINE THE PRECLINICAL PHARMACODYNAMICS/ PHARMACOKINETICS OF AIT-082, (2) CONDUCT PRECLINICAL TOXICOLOGICAL TESTING, AND (3) CONDUCT ADDITIONAL PRECLINICAL STUDIES ON THE MECHANISM OF ACTION OF AIT- 082. THE AIM OF PHASE II WILL BE TO FILE AN IND APPLICATION AND TO ESTABLISH THE CLINICAL SAFETY AND EFFICACY OF AIT-082.

Technology keywords

Not reported

Agency intelligence

Department of Health and Human Services

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