SBIR/STTR Research Award
Directed Delivery of Growth Factors to the CNS
Award amount
$290,174Program and phase
SBIR · Phase IAward year
2005Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- TERA BIOTECHNOLOGY CORPORATION
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- PHS2005-2
- Topic code
- Not reported
Research abstract
DESCRIPTION (provided by applicant): Certain proteins, like growth factors have significant potential to treat neurodegenerative disease. Accordingly, it should be possible to stimulate the growth of endogenous progenitor stem cells so that they could enhance the natural course of injury repair. Unfortunately, the blood brain barrier forms a significant hurdle that limits the clinical utility of most peptides. We propose to apply principles of medicinal biology and combinatorial pharmacology to improve the delivery of growth factors to the brain and describe a comprehensive strategy to address a major problem in the development of CNS biotherapeutics: drug delivery to the brain.
Technology keywords
Not reported