Human Microdialysis

Microdialysis is used extensively and successfully in animal studies to measure key biochemicalparameters in the brain. With appropriate innovations in the design of the microdialysis probe an themonitoring of key analytes (described in the present application), this technology is ready for diagnosticand possibly therapeutic application in humans. The use of microdialysis probes in humans will accessa number of key biochemical measurements, improving the quality of health are possible in neurosurgery.Phase I will make proprietary advances in the design, construction, and use of microdialysis devices forimplementation in humans. The devices will be tested extensively, a design selected for Phase 2 testing,and patent applications will be filed. The results achieved during this initial research period will lay thefoundation for the production of model suitable for FDA approval, obtaining the human data necessaryfor such approval being the goal of Phase 2.