SBIR/STTR Research Award
IGF OT IGF A MULTIFUNCTIONAL REUSABLE AND AUTOMATED MICROFLUIDIC SMART PLATE FOR HIGH THROUGHPUT LIVE CELL ASSAYS
Award amount
$230,000Program and phase
SBIR · Phase IAward year
2016Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- CAIRN BIOSCIENCES INC
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- LWZWY2J1M2J4
- Solicitation number
- Not reported
- Topic code
- NIDA
Research abstract
This project aims to design and develop a multifunctional reusable and automated microfluidic smart plate for high throughput live cell assays This system will combine a microfluidic multi well chamber array and an environmental measurement system into a single device enabling high accuracy and closed loop control over experiment environmental factors Existing environmental control chambers are large physically cumbersome and expensive to obtain while being designed for a single microscope type and configuration Our device is a singular solution for live cell time lapse and environmental response studies With a single device researchers can inject stimuli monitor and alter environmental factors capture high numerical aperture images and measure confluence The device will make use of commonly available components and manufacturing methods enabling replication by a wide range of interested parties from research labs to industry manufacturers
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- A MICROFLUIDIC AND MACHINE LEARNING-ENABLED SMARTLAB FOR AUTONOMOUS REMOTE EXECUTION AND ITERATION OF MULTISCALE LIVE CELL ASSAYS FOR DRUG DISCOVERY
- High-throughput profiling of compound abuse liabilities and identification of addiction-related drug targets using an iPSC-enabled platform
- Multiplexed high-content assay for toxicity profiling using live iPSC-derived cardiomyocyte lines with lineage-specific barcoding
- IGF OT IGF MULTIPLEXED HIGH CONTENT ASSAY FOR TOXICITY MECHANISMS AND PHENOTYPES IN LIVE IPSC DERIVED CARDIAC CELLS
- SBIR Phase II: A novel multicolor cell line engineering platform that enables high-throughput microscopy-based screening of living cells for drug discovery
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Wearable Wireless Respiratory Monitoring System that Detects and Predicts Opioid Induced Respiratory Depression
- Building and testing the Life Enhancement and Advocacy Programming digital training tool (LEAPLink) to better serve people with lived experience of homelessness and substance use disorder
- A digital intervention to decrease self-stigma among pregnant and postpartum women with opioid use disorder
- Development of medication for the treatment of respiratory depression due to opioid (prescribed or illicit) overdose/multidrug (polysubstance) overdose in a hospital or community setting.
- Creation and Validation of the Dose-Opioid-Source Evaluation tool (DOSE) - a Robust Opioid Use Clinical Outcome Assessment for Qualification as an FDA Medical Device Development Tool (MDDT)
Research funding history
9 SBIR/STTR records share this UEI (2015–2021). Reported award amounts total $5,740,087. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Health and Human Services, National Science Foundation