SBIR/STTR Research Award
A STRUCTURE ACTIVITY WORKSTATION FOR DRUG DESIGN
Award amount
$467,413Program and phase
SBIR · Phase IIAward year
1992Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- Molecular Solvometrics, Inc.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
A COMPUTER SOFTWARE PACKAGE IS UNDER DEVELOPMENT FOR DRUG DESIGN UTILIZING CLASSICAL AND NEW INNOVATIONS IN QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIPS (QSAR). A PRACTICAL AND USER-FRIENDLY COMPUTER WORK STATION IS BEING DESIGNED TO GIVE SPECIFIED TYPE ACTIVITIES FOR TARGET MOLECULAR STRUCTURES IN SECONDS OR LESS. SPECIFIC PROCESSES ARE INCORPORATED FOR CONSIDERING THE EXCHANGE OF NON-DIRECTIONAL SOLVATION FORCES BETWEEN A PHARMACEUTICAL STRUCTURE AND BULK WATER OR BLOOD PLASMA FOR SPECIFIC GEOMETRICALLY-CONSTRAINED FORCES ACTING AT AN ENZYME OR OTHER ACCEPTOR SITE.
Technology keywords
Not reported